With the Emperor Constantine, the role of Christianity changed dramatically in the Roman Empire. Large churches were built and adorned with mosaics. Many of the images found in the catacombs, also changed in their designs. But basically the image of the Persian Magi remained the same. They were still considered the historical Magi.

From the 5th Century A.D. we have this mosaic in the Basilica of St. Mary Major in Rome. The Magi, dressed in Persian attire, are offering their gifts to a slightly older Christ Child, seated on an imperial throne. Perhaps this indicates the Church's coming of age under Constantine.

In the 6th Century A.D. the Byzantine style of mosaics continued to be used. Here we have the famous depiction of the Magi from the Church of San Apollinare in Ravenna, Italy. The three Zoroastrian priests are shown as representing the three ages of humanity.

In the Church of San Vitale in Ravenna, Italy, again from the 6th Century A.D., there is a mosaic of the Empress Theodora donating the Church of San Vitale to Christ. To signify that her gift was similar to the Magi's, we have the image of the three Magi on the hem of her robe.

Again, from the 6th Century A.D., we have this ivory Gospel book cover.

This ivory plaque, also from the 6th Century A.D., is from Syria.

From the 7th Century A.D. we have this silver ampulla from Palestine. It depicts the Virgin and Child in the center, with the Magi to the left and the shepherds to the right. This was a flask used by pilgrims. It is believed that the design on this flask was based on the mosaic that adorned the entrance of the Church of the Nativity in Bethlehem. That mosaic probably saved the church from destruction in 614 A.D. In that year, the Persians, under Chosroes II devastated Palestine and destroyed many churches, including the Church of the Holy Sepulchre in Jerusalem. But when they reached Bethlehem, they found the mosaic of the Adoration of the Magi above the entrance of the Church of the Nativity. According to a letter written during the Synod of Jerusalem, "on their arrival at Bethlehem they were amazed at the picture of the Persian Magi, their fellow-countrymen. In respect and affection for their ancestors, whom they venerated as if they had been alive, they spared the church.

This two ivory are also dated from the 7th Century A.D.

In the 8th Century A.D. we have developing art forms. This is part of an altar frontal in San Martino at Cividale.

Also from the 8th Century A.D. is this Anglo-Saxon box, carved from ivory.